Tuesday, December 6, 2011

Clinical Features of Pustulotic Arthro-Osteitis

Jun-ichi Fukushi and colleagues reported clinical features of Pustulotic arthro-osteitis. Palmoplantar pustulosis (PPP) and anterior chest wall lesions (81%) are the leading symptoms. Peripheral arthritis and spinal lesions were observed, but did not add to make the diagnosis. Twenty-six pastients (48%) were treated with NSAIDs alone. Salazosulfapyridine was used in 9 patients, who did not respond to NSAIDs, whereof 6 showed improvement of pain and a decrease in CRP.
To my dismay the authors didn’t tell, what kind of treatment they used with the 3 non-responders. We would use a biphosphonate, but that’s OT and open to discussion.

[SUN] 540
Clinical Features of Pustulotic Arthro-Osteitis.
Jun-ichi Fukushi, Yasuharu Nakashima, Ken Okazaki, Taro Mawatari, Masanobu Ohishi, Yasutaka Tashiro and Yukihide Iwamoto.
Kyushu University, Fukuoka, Japan
Conclusion: We reviewed 54 cases with PAO. The skin lesions preceded, or occurred simultaneously, with arthro-osteitis in most of the cases. In addition to anterior chest wall lesions, which were the most common finding, peripheral arthritis and spinal lesions were also observed in about 20% of the cases. NSAIDs were effective in about half of all the cases. Salazosulfapyridine and oral steroids may therefore be a potentially useful treatment regimen for cases refractory to NSAIDs.

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